Clomiphene Citrate Challenge Test

The Clomiphene Citrate Challenge Test (CCCT) is a sensitive way to measure a woman’s “ovarian reserve”, that is, whether she has sufficient eggs within her ovaries likely to respond to ovarian stimulating hormones. CCCT is a more sensitive alternative to the simple measurement of blood follicular stimulating hormone (FSH) and Estradiol levels on day 2 or day 3 of the menstrual cycle. Results of this test will help you and your physician evaluate your ovarian reserve and adjust your controlled ovarian hyperstimulation plan accordingly.

Cycle Instructions

Day 1 Beginning of menses.
Day 2 or 3 FSH and Estradiol Blood Test.
Day 5 – 9 Take Clomiphene 100 mg a day. (Two 50 mg tablets to be taken together at anytime of the day. Be consistent with time.)
Day 10 FSH Blood Test.

You may combine this test of your ovarian reserve with an intrauterine insemination to take advantage of the eggs recruited with the clomiphene. You can discuss this option with your coordinator before your cycle begins.